1190989-12-8Relevant articles and documents
Functionalization of dihalophenylboronic acids by deprotonation of their N-butyldiethanolamine esters
Durka, Krzysztof,Kurach, Pawel,Lulinski, Sergiusz,Serwatowski, Janusz
experimental part, p. 4325 - 4332 (2011/02/22)
Deprotonative lithiation of various 6-butyl-2-(dihalophenyl)-(N-B)-1,3,6,2- dioxazaborocanes (N-butyldiethanolamine esters of dihalophenylboronic acids) was investigated. It was found that selective transformations can be best achieved by use of LDA as the lithiating reagent. The reactivities of these compounds vary significantly, depending on the natures and positions of the halogen atoms. The resultant boron-lithium bimetallic intermediates were subjected to reactions with electrophiles to afford functionalized halogenated arylboronic acids.
