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CAS

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Lysozyme belongs to a group of enzymes that are known as glycoside hydrolases. It is found in animal tissues, organs, serum as well as in tears, nasal secretions, cervical mucus, and the white of avian eggs. Lysozyme breaks the carbonhydrate chains of the bacterial skin, destroying the structural integrity of the cell wall. Thereby, it has antibacterial properties and was one of the first antibiotics studied by Sir Fleming, the discover of penicillin. Lysozyme is used either alone or in combination with other synergic compounds as an excellent preservative against many food spoiling microorganisms for fruits & vegetables, tofu & bean curd, seafood & meats, wines & sakes. Organic wines use it to reduce sulfites. It is used in non-pasteurized beer. It has been added to baby formula (to aid digestibility) and gastrointestinal treatments for the elderly.? Lysozyme is used in skin care, to cure and prevent acne and bed sores, as well as in optical, dental, and oral conditions.

12650-88-3

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12650-88-3 Usage

References

[1] http://ase.tufts.edu/biology/MolecVisual/bio152/rightlyso.html#top [2] http://www.xtend-life.com/information/ingredients/lysozyme [3] http://www.bioseutica.com/products/lysozyme

Uses

Different sources of media describe the Uses of 12650-88-3 differently. You can refer to the following data:
1. Catalyzes the hydrolysis of peptidoglycans found in bacterial cell walls. Lysozyme catalyzes is utilized for the hydrolysis of peptidoglycans found in bacterial cell walls. It is used as a precursor in the production of spheroplasts. It is also used as a preservative against many food spoiling microorganisms. It is used in skin care in order to cure and prevent acne and bed sores, dental and oral conditions. It is used for lysing E. coli and Streptomycetes for extraction purposes such as extracting group specific antigen. Further, it is used in non-pasteurized beer.
2. Lysozyme has been used in the monitoring of transcription by real-time -PCR and sample preparation.
3. Enzyme breaks down the cell walls of bacteria; used to prepare spheroplasts.

General Description

Lysozyme from chicken egg white, is a protein that can show broad spectrum of antibacterial activity against gram positive and gram negative bacteria. Its antimicrobial activity can be enhanced by pretreatment of the target microbial cells with chelating agents like ethylenediaminetetraacetic acid (EDTA).

Flammability and Explosibility

Nonflammable

Biochem/physiol Actions

Lysozyme hydrolyzes β(1→4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrin. Gram-positive cells are quite susceptible to this hydrolysis as their cell walls have a high proportion of peptidoglycan. Gram-negative bacteria are less susceptible due to the presence of an outer membrane and a lower proportion of peptidoglycan. However, these cells may be hydrolyzed in the presence of EDTA that chelates metal ions in the outer bacterial membrane.The enzyme is active over a broad pH range (6.0 to 9.0). At pH 6.2, maximal activity is observed over a wider range of ionic strengths (0.02 to 0.100 M) than at pH 9.2 (0.01 to 0.06 M).

Check Digit Verification of cas no

The CAS Registry Mumber 12650-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,6,5 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 12650-88:
(7*1)+(6*2)+(5*6)+(4*5)+(3*0)+(2*8)+(1*8)=93
93 % 10 = 3
So 12650-88-3 is a valid CAS Registry Number.

12650-88-3 Well-known Company Product Price

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  • Sigma-Aldrich

  • (34046)  Lysozymefromchickeneggwhite  VETRANAL™, analytical standard

  • 12650-88-3

  • 34046-100MG-R

  • 1,166.49CNY

  • Detail

12650-88-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Lysozyme from chicken egg white

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:12650-88-3 SDS

12650-88-3Upstream product

12650-88-3Downstream Products

12650-88-3Related news

Effectiveness of Lysozyme (cas 12650-88-3) coatings and 1-MCP treatments on storage and preservation of kiwifruit08/20/2019

The objective of the present study was to investigate the effectiveness of lysozyme coatings and 1-MCP on storage and preservation of kiwifruit stored at 4?±?1?°C and 90–95% RH for 20 d. Ethylene production, respiratory rate, decay incidence, weight loss, firmness, chlorophyll, soluble solid,...detailed

Characterization of the role of ybgC in Lysozyme (cas 12650-88-3) resistance of Salmonella Enteritidis08/19/2019

The ybgC gene (encoding for acyl-CoA thioesterase) was shown to play a crucial role in the survival of Salmonella Enteritidis (S. Enteritidis) in egg white in our previous study. In this study, the resistance mechanisms of S. Enteritidis wild-type, △ybgC mutant, and △ybgC-C complemented strain...detailed

Lysozyme (cas 12650-88-3) sorption by pure-silica zeolite MFI films08/18/2019

Nanostructured, porous materials, like zeolites, have been suggested as possible materials for biomedical applications in implantable device coatings, tissue engineering, and drug delivery systems due to their unique interactions with biomolecules and biological environments. Here, the fundament...detailed

Purification of Lysozyme (cas 12650-88-3) from chicken egg white using diatom frustules08/17/2019

A nontoxic chromatographic matrix, with low cost and high adsorption capacity, is always a major goal for therapeutic protein purification. In this study, the frustules from two cultured diatoms, Nitzschia bilobata (AQ1) and Psammodictyon panduriforme (NP), were investigated as cation exchange m...detailed

Lysozyme (cas 12650-88-3) encapsulated gold nanoclusters for probing the early stage of Lysozyme (cas 12650-88-3) aggregation under acidic conditions08/16/2019

Protein aggregation can lead to several incurable amyloidosis diseases. The full aggregation pathway is not fully understood, creating the need for new methods of studying this important biological phenomenon. Lysozyme is an amyloidogenic protein which is often used as a model protein for studyi...detailed

Bacterial Killing Is Enhanced By Exogenous Administration Of Lysozyme (cas 12650-88-3) In The Lungs08/15/2019

ABSTRACTObjective: Lysozyme, a 14-kDa protein, is one of the most abundant antimicrobials in the lungs. Its concentration in airway surface sufficient to kill several bacterial pathogens in vitro. The purpose of this study was to determine if administration of exogenous lysozyme would further en...detailed

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