37797-30-1Relevant articles and documents
Azobenzene-Based Macrocyclic Arenes: Synthesis, Crystal Structures, and Light-Controlled Molecular Encapsulation and Release
Liu, Yuezhou,Wang, Hongliang,Liu, Peiren,Zhu, Huangtianzhi,Shi, Bingbing,Hong, Xin,Huang, Feihe
, p. 5766 - 5770 (2021)
Azobenzene (azo)-based macrocycles are highly fascinating in supramolecular chemistry because of their light-responsiveness. In this work, a series of azo-based macrocyclic arenes 1, 2, 3, and 4, distinguished by the substituted positions of azo groups, i
Azobenzene-Bridged Expanded "Texas-sized" Box: A Dual-Responsive Receptor for Aryl Dianion Encapsulation
Chi, Xiaodong,Cen, Wanglai,Queenan, Jack A.,Long, Lingliang,Lynch, Vincent M.,Khashab, Niveen M.,Sessler, Jonathan L.
, p. 6468 - 6472 (2019)
We report an expanded "Texas-sized" molecular box (AzoTxSB) that incorporates photoresponsive azobenzene bridging subunits and anion recognition motifs. The shape of this box can be switched through light induced E ? Z photoisomerization of the constituen
A Paclitaxel Prodrug Activatable by Irradiation in a Hypoxic Microenvironment
Chen, Guang,Hu, Xiuli,Jing, Xiabin,Liu, Shi,Pei, Qing,Xia, Rui,Xie, Zhigang,Zhou, Shiyu
, p. 23198 - 23205 (2020)
The innate hypoxic microenvironment of most solid tumors has a major influence on tumor growth, invasiveness, and distant metastasis. Here, a hypoxia-activated self-immolative prodrug of paclitaxel (PTX2-Azo) was synthesized and encapsulated by
Switching Process Consisting of Three Isomeric States of an Azobenzene Unit
Adam, Abdulselam,Haberhauer, Gebhard
, p. 9708 - 9713 (2017)
Azobenzene and its derivatives are among the most commonly used switching units in organic chemistry. The switching process consists of two states, in which the trans isomer has a stretched and the cis isomer a compact form. Here, we have designed a syste
Palladium Nanoparticles on Silica Nanospheres for Switchable Reductive Coupling of Nitroarenes
Lakshminarayana, Bhairi,Manna, Arun Kumar,Satyanarayana,Subrahmanyam, Ch.
, p. 2309 - 2321 (2020/02/18)
Abstract: In this study, we synthesized a robust and sustainable Pd/SiO2 nanospheres catalyst. Further, its catalytic activity was demonstrated for the direct reductive coupling of nitroarenes under mild conditions. While the reaction with Pd nanoparticles on other supporting materials such as modified carbon materials and TiO2, under similar conditions, resulted formation of amines exclusively. Therefore, it was confirmed that the SiO2 was found to be the best supporting material towards the selective reductive coupling of nitroarenes. Also, the catalyst could be recycled up to five cycles with a marginal loss of product yield ( 2% yield). Graphic Abstract: [Figure not available: see fulltext.].
Tandem selective reduction of nitroarenes catalyzed by palladium nanoclusters
Yan, Ziqiang,Xie, Xiaoyu,Song, Qun,Ma, Fulei,Sui, Xinyu,Huo, Ziyu,Ma, Mingming
supporting information, p. 1301 - 1307 (2020/03/11)
We report a catalytic tandem reduction of nitroarenes by sodium borohydride (NaBH4) in aqueous solution under ambient conditions, which can selectively produce five categories of nitrogen-containing compounds: anilines, N-aryl hydroxylamines, azoxy-, azo- and hydrazo-compounds. The catalyst is in situ-generated ultrasmall palladium nanoclusters (Pd NCs, diameter of 1.3 ± 0.3 nm) from the reduction of Pd(OAc)2 by NaBH4. These highly active Pd NCs are stabilized by surface-coordinated nitroarenes, which inhibit the further growth and aggregation of Pd NCs. By controlling the concentration of Pd(OAc)2 (0.1-0.5 mol% of nitroarene) and NaBH4, the water/ethanol solvent ratio and the tandem reaction sequence, each of the five categories of N-containing compounds can be obtained with excellent yields (up to 98%) in less than 30 min at room temperature. This tunable catalytic tandem reaction works efficiently with a broad range of nitroarene substrates and offers a green and sustainable method for the rapid and large-scale production of valuable N-containing chemicals.
System and method for reversible photo-controlled gene silencing
-
Page/Page column 4; 21; 22, (2020/08/07)
In one aspect, a chemically-modified siRNA for reversible photo-controlled gene silencing is provided. In one embodiment, one or more nucleotides the sense strand of the siRNA are replaced with a spacer comprising an azobenzene or derivative thereof. The
Unexpected observations during the total synthesis of calothrixin B-sodium methoxide as a source of hydride
Bhosale, Shrikar M.,Momin, Aadil A.,Kunjir, Shrikant,Rajamohanan,Kusurkar, Radhika S.
supporting information, p. 155 - 162 (2014/01/06)
During the total synthesis of calothrixin B, various novel and unexpected results were noticed such as cleavage of C-N bond in imine using sodium cyanoborohydride, sodium methoxide as a hydride source for reduction, deformylation in the presence of bromine, and deacylation using ceric ammonium nitrate (CAN). A detailed mechanism has been proposed for the unexpected results and a few of them are generalized. Temperature dependent NMR studies have been carried out for confirmation of the structure of one of the intermediates in the synthetic sequence.
