化學(xué)配方數(shù)據(jù)庫(kù)
| 配方類(lèi)型： |
COSMETICS AND DRUGS |
| 配方說(shuō)明： |
Corticosteroid-Antibiotic Topical Lotion |
| 配方組成： |
Distilled Water, q.s./10 liters
Neomycin Sulfate (0.5 w/v)/50
Isopropyl Palmitate/130
Polyethylene Glycol 400 Monostearate/250
Stearic Acid/150
Hydrocortisone (0.5 w/v)/50
Sodium Benzoate (preservative)/20
Propylene Glycol/1000 |
| 配制方法： |
Dissolve the hydrocortisone with stirring and heating (65C) in the propylene glycol. Cool the propylene glycol solution to 50C, add with stirring the stearic acid, PEG-400 monostearate, and isopropyl palmitate, and filter. Heat 6.5 liters of distilled water to 50 and dissolve with stirring the sodium benzoate and neomycin sulfate, and filter. While maintaining both solutions at 50C, add with stirring the aqueous solution to the propylene glycol solution, and bring to final volume with water. Pass the mixture through a colloid mill at 40C and conduct the filling operation while continuously stirring. |
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